The Nobel Prize in medicine awarded for work on the human immune system

T cells protect the body from infection, while the thymus eliminates those that mistakenly attack healthy tissue. (iStock)

STOCKHOLM (AP) — Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi won the Nobel Prize in medicine Monday for their discoveries concerning peripheral immune tolerance. Brunkow, 64, is a senior program manager at the Institute for Systems Biology in Seattle. Ramsdell, 64, is a scientific adviser for Sonoma Biotherapeutics in San Francisco. Sakaguchi, 74, is a distinguished … Read more

Local dental SEO: Put your practice on the map

Google Maps results capture the majority of clicks from patients searching for a new dentist. (iStock)

Dental patients no longer flip through phone books or rely only on referrals. They research online, reading reviews, comparing services, and searching Google for the most convenient clinic. If your dental practice doesn’t appear in those local searches, you’re missing out on a steady flow of new patients. Google’s local algorithm prioritizes dentists near the … Read more

The periodontal network

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When a 45-year-old patient presents with Stage IV, Grade C periodontitis alongside unexplained cervical lymphadenopathy, the question is not just about pocket depths. It is about recognizing that you are looking at a biological network in distress, one where local inflammation has activated systemic pathways that extend far beyond the gingival margin. This scenario is not hypothetical. … Read more

‘First’ study says a heart attack might be an infectious disease in another link to oral bacteria

New research has found DNA from oral bacteria inside arterial plaques, suggesting heart attacks may partly be triggered by infection. (iStock)

Yet another study is strengthening the connection between oral and overall health — this time suggesting that heart attacks may partly be an infectious disease. Researchers from Finland and the UK, writing in the Journal of the American Heart Association (JAHA), report they found bacterial DNA from common oral species inside arterial plaques. Their findings, … Read more

Dentsply Sirona World 2025: Celebrating legacy and driving innovation

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Dentsply Sirona World 2025 returned to the MGM Grand in Las Vegas, delivering a remarkable event filled with clinical education, networking, and entertainment for dental professionals. This year’s program highlighted the importance of Connected Dentistry while celebrating 40 years of CEREC—the chairside digital workflow that has transformed single-visit dentistry. At the heart of this evolution … Read more

What Dentalcorp’s $2.2B sale means for dentists in Canada

“Oral Science is a Canadian success story much like our own,” says René Goehrum, president and CEO of BioSyent. (iStock)

The Canadian dental industry is entering a new chapter. Dentalcorp Holdings Ltd., the country’s largest dental services organization with more than 550 practices, has agreed to be acquired by U.S. private equity firm GTCR in a transaction valued at C$2.2 billion. Once complete, Dentalcorp will no longer be publicly traded on the Toronto Stock Exchange … Read more

Half of Canadians say they would smile more with healthier teeth, survey finds

About 84 per cent of Canadians believe a healthy smile boosts self-esteem and overall well-being. (iStock)

Oral health is increasingly linked not only to overall health, but also to confidence and daily behaviours like smiling. A new survey released Friday found that more than half of Canadians say they would smile more if their teeth were healthier or better looking. The poll, conducted in August by Leger Marketing for 123Dentist, surveyed … Read more

Minister says CDCP ‘a work in progress’ as half of 5.2M approved patients haven’t seen a dentist

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Nearly half of the 5.2 million Canadians approved under the federal Canadian Dental Care Plan (CDCP) have yet to see a dentist, Health Minister Marjorie Michel acknowledged Thursday. “It’s still a new program,” Michel told reporters when pressed on the uptake rate. “It’s like, you can go to your doctor, and you don’t feel the … Read more

Alberta’s dentists are in ‘limbo’ amid federal vs provincial dental programs ‘confusion’

Ontario’s new legislation would open the door for dental professionals across Canada to practise in the province with fewer barriers. (iStock)

Alberta dentists are caught in “limbo” as confusion persists over how the federal Canadian Dental Care Plan (CDCP) is overlapping with the province’s existing coverage and when Ottawa’s program will end for Albertans. “Without a time frame, our dentists are in limbo with respect to knowing how to encourage patients, which plan to utilize. Should … Read more

NYU researchers develop zinc-based treatment to fight tooth decay without drilling or staining

Tooth decay in permanent teeth is the world’s most common health condition. (iStock)

New York University scientists are developing a zinc-based treatment for cavities that could eliminate the need for drilling and filling, while also avoiding the black staining that limits use of existing products. Marc Walters, a professor of chemistry at NYU, has created a colourless compound called zinc tetramine difluoride, which forms zinc oxide crystals deep … Read more

Chemical banned in EU nail polishes still used in dental treatments in Portugal, says group

The ban has unsettled nail-care professionals, who now face the challenge of disposing of existing stock and reformulating products without TPO. (iStock)

A substance recently banned from gel nail polishes across the European Union is reportedly still in use in certain dental procedures in Portugal — raising concerns that regulatory action could expand to medical-device materials, Euro News reported Friday. The chemical, Trimethylbenzoyl Diphenylphosphine Oxide (TPO), acts as a photoinitiator, triggering polymerization (hardening) of gels and resins … Read more

ADA defends acetaminophen safety after Trump links Tylenol to autism

The ADA recommends nonsteroidal anti-inflammatory drugs, with or without acetaminophen, as first-line treatments for acute dental pain in adolescents 12 and older. (iStock)

The American Dental Association is pushing back against claims from the Trump administration that Tylenol could be linked to autism, stressing that peer-reviewed science shows acetaminophen is safe. “Acetaminophen is well studied and proven to be safe for use in pregnancy and is one of the few medicines available to pregnant individuals for pain relief … Read more

U.N. health goals weakened as sugar, other labelling warnings removed; U.S. objects to final plan

The U.N. final version of the declaration keeps language on universal health coverage and stronger primary care but drops earlier proposals for “health taxes” on tobacco, alcohol and sugar. (iStock)

A U.N. political declaration on noncommunicable diseases, negotiated over months and backed by most member states, failed to win formal endorsement Thursday after the United States blocked its adoption by consensus at a high-level General Assembly session. Shortly after its release, U.S. Health Secretary Robert F. Kennedy Jr. said Washington would formally object, arguing the … Read more

Dentalcorp agrees to $2.2B takeover by U.S. private equity firm GTCR

“This collaboration represents a pivotal moment for dentistry,” said Ryan Hungate, chief clinical and strategy officer at Henry Schein One (iStock)

Dentalcorp Holdings Ltd., Canada’s largest dental services provider, said Friday it has agreed to be acquired by U.S. private equity firm GTCR LLC in a deal valued at C$2.2 billion. The announcement comes as Dentalcorp carries an estimated $1.1 billion in total debt and a debt-to-equity ratio of about 60 per cent, according to financial … Read more

‘First’ study links oral bacteria to Parkinson’s disease

Parkinson’s disease is a common brain disorder marked by tremors, muscle stiffness and slowed movement. (iStock)

A bacterium best known for causing tooth decay has been linked to Parkinson’s disease, in what researchers call the first study to show a direct microbial pathway driving the condition. The study, published this month in Nature Communications, was led by researchers in South Korea at POSTECH and Sungkyunkwan University, with collaborators from Seoul National … Read more

U of T researchers test probiotics in everyday foods like yogurt to fight childhood cavities

Researchers identified Streptococcus salivarius — a naturally occurring oral bacterium also present in breast milk — as a promising candidate for a synbiotic formula to prevent cavities in children. (iStock)

University of Toronto researchers are testing whether probiotics infused into common foods such as milk or yogurt could help prevent childhood cavities — one of the world’s most widespread chronic diseases. Led by dentistry professor Céline Lévesque, the team is using synbiotics — a combination of probiotics and prebiotics — to determine if beneficial bacteria … Read more

Canadian, U.S. lenders boost Corus Orthodontists’ access to $250M in credit

Founded in 2019, Corus has more than 75 locations across 13 U.S. states and five Canadian provinces. (iStock)

Corus Orthodontists, a North American orthodontic partnership network, said Wednesday it has increased its secured syndicated credit facility to C$250 million from C$175 million. The facility, provided through a syndicate of Canadian and U.S. lenders, also includes an uncommitted accordion feature that allows for expansion up to C$325 million. The Canadian Imperial Bank of Commerce … Read more

UB researcher wins nearly $1M NIH award to use AI to fight against gum disease

Li’s project uses a form of advanced machine learning called manifold learning, which distills complex data into simplified patterns. (iStock)

A University at Buffalo postdoctoral researcher will use artificial intelligence (AI) to uncover how gum disease develops and progresses. Lu Li, a postdoctoral associate in the School of Dental Medicine’s Department of Oral Biology, has received a $993,098 Pathway to Independence Award (K99/R00) from the U.S. National Institutes of Health (NIH). The five-year grant will … Read more

Dentalcorp declares third consecutive dividend

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Dentalcorp Holdings Ltd. has declared a dividend of $0.025 per share, payable Oct. 21, 2025, to shareholders of record as of Oct. 2. The company will release its third-quarter 2025 results on Nov. 6, before markets open. This marks Dentalcorp’s third consecutive quarterly dividend since its board authorized an inaugural payout in March 2025. At … Read more

Dental program improving, industry says, but misconceptions about ‘free’ care persist

Former prime minister Justin Trudeau and former health minister Mark Holland repeatedly referred to the Canadian Dental Care Plan as “free dental care,” as did the New Democrats, who pushed for the program’s creation. (iStock)

The rollout of the national dental care program is improving, industry representatives say — but political statements are still driving a misconception among patients that the program will cost them nothing. “When the plan was initially announced, the government of the day continually talked about free dentistry, free dental care,” said Dr. Bruce Ward, president of the Canadian Dental Association. Former … Read more