Oral Lesions

Oral Cancer and the Race Against Time: Use of Psoriasin (S100A7) as a Predictive Marker to Enhance Assessment of Cancer Risk in Oral Lesions

Introduction Oral squamous cell carcinoma (OSCC) is a potentially debilitating and deadly disease, particularly when diagnosed at an advanced stage.1 Early detection drastically improves prognostic outcomes, making diagnosis a race against time.2 Most cases of OSCC begin as a precursor lesion or condition, classified by the World Health Organization (WHO) as an “oral potentially malignant … Read more

Dentists Could Play a Key Role in Identifying Domestic Violence Cases: Study

Patients visiting the dentist for lesions to the jaw and teeth could be victims of domestic violence, U.S. researchers warn. Oral biomarkers that might signal domestic violence include tears, fractures, breaks, and chips in the teeth and mouth. Published in the Journal of Aggression, Maltreatment and Trauma in mid-April, the article reports that up to 75 per … Read more

Psoriasin: A New Biomarker in the Identification of Cancer Risk in Oral Lesions

Introduction Approximately 90% or more of oral cancers are squamous cell carcinomas (OSCCs). These often begin as potentially malignant oral lesions such as a white patch (leukoplakia; Fig. 1), or red patch (erythroplakia; Fig. 2), 1 which progress to an invasive cancer.1 Although the term “premalignant” is widely used for such lesions, the term “potentially … Read more