General Dentistry: Table 2: Adverse Orofacial Reactions to Tricyclic and Related Antidepressants (TCAs)

Medication	xerostomia	sialadenitis	dysgeusia	stomatitis	gingivitis	glossitis	edema	tongue	bruxism	Misc.
Amitriptyline	+	+	+	+	0	0	+	+	0	0
											caries, cheilitis,
Clomipramine	+	+	+	+	+	+	0	0	0	dysphagia, oral ulcers,
											halitosis. sinusitis
Desipramine	+	+	+	0	0	0	+	+	0	facial edema
Doxepine	+	0	+	+	0	0	0	0	0	0
Imipramine	+	+	+	+	0	0	+	+	0	facial edema
Maprotiline	+	+	+	+	0	0	0	+	0	dysphagia
Nortriptyline	+	+	+	+	0	0	+	+	0	facial edema
Protriptyline	+	+	+	0	0	0	+	+	0	facial edema
Trazodone	+	0	+	0	0	0	0	0	0	sinusitis