Gum disease may increase gastric cancer risk by 25 per cent, study finds

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Gum disease may raise the risk of developing gastric cancer by up to 25 per cent, according to a large-scale study published in BMC Medicine. The research, led by Southeast University’s School of Public Health in China, analysed health data from nearly six million adults in Sweden. It is the first study to use sibling-controlled … Read more

Study links lower oral microbiome turnover to higher cavity risk in children with HIV exposure

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The mouth is the second most diverse microbial system in the human body after the gut—but researchers at Penn Dental Medicine say it behaves very differently when it comes to long-term health. In a study published July 16 in Microbiome, researchers compared the oral microbiomes of Nigerian children living with HIV, those exposed to the … Read more

AI shows promise in detecting early childhood cavities, study finds

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A review of 21 studies conducted between 2014 and 2024 suggests that artificial intelligence (AI), particularly deep learning (DL) algorithms, shows strong potential in detecting and predicting early childhood caries (ECC). Published July 26 in Nature, the study found that DL algorithms—models based on complex neural networks that mimic how the human brain detects patterns … Read more

Study finds tooth nerves are more than pain sensors — they’re protectors

Human tooth structure showing dental nerves. (iStock)

A new University of Michigan study has found that tooth nerves are more than just pain detectors — they also play a protective role that could have major implications for future dental treatments and innovations. “When we consider regenerating a tooth pulp, we need to bring back the nerves.” In a peer-reviewed paper published in … Read more

Study finds no strong link between diet and cavities in young children from low-income families

New study finds no clear link between sugary snacks and cavities in young children

While sweet drinks and snacks aren’t recommended for children, a new study has found no significant association between their consumption patterns and the development of early childhood caries (ECC) in low-income children under the age of two. Published July 13 in BMC Oral Health, the study followed 127 Medicaid-eligible children from birth at two university-affiliated … Read more

Needle-free flu vaccine delivered by dental floss shows promise — in mice

In their experiment, the researchers flossed 50 mice with the floss laced with the vaccine every 2 weeks. (iStock)

Engineers have developed a novel method to deliver vaccines without needles — using dental floss. In a study published July 22 in Nature Biomedical Engineering, researchers showed that vaccine-laced floss can deliver therapeutics through the junctional epithelium, a thin, porous tissue where the gums attach to the teeth, also known as the base of the … Read more

Study: Childhood abuse increases risk of developing caries in children ages 7 to 10

“These findings reinforce the importance of early intervention—not just from a psychological standpoint, but also for children’s physical and oral health,” the authors stated.

Drawing data from 7,633 children in Bristol, England, a recently published study shows that childhood abuse can increase the risk of developing caries in children ages 7 to 10. “This knowledge can help dentists identify vulnerable children or families during routine dental visits,” the researchers wrote in their paper, published in the Journal of Dentistry. … Read more

Dental surgeon’s new geometric theory may solve 500-year-old Vitruvian Man mystery

Da Vinci’s Vitruvian Man encodes blueprint of human evolution, says London dental surgeon. (Photo courtesy of Rory Mac Sweeney)

Drawing on his interdisciplinary work in dental anatomy, geometry and human evolution, London-based dental surgeon Dr. Rory Mac Sweeney has proposed a new interpretation of the geometry behind Leonardo da Vinci’s Vitruvian Man. Historians and mathematicians have long debated the meaning of the famous sketch, including why da Vinci drew the man inside both a … Read more

Study links poor oral health to abnormal blood test results in older adults

A study of 118 people aged 50 and older who underwent routine medical check-ups found a link between oral health and blood test results. (iStock)

A new Japanese study has found that older adults with abnormal blood test results may also have declining oral health—suggesting a potential link between oral function and the risk of lifestyle-related diseases. The study, published online in the Journal of Oral Rehabilitation on April 17, 2025, was led by Professor Mitsuyoshi Yoshida, chair of the … Read more

Tufts researchers develop ‘smart’ dental implant to mimic natural teeth — next step, testing the brain

Subhashis Ghosh, Dr. Jake Jinkun Chen and Siddhartha Das, co-authors of the study, at the Tufts Biomedical Research and Public Health Building. (Photo courtesy Jenna Schad/Tufts University)

Tufts University scientists are developing a new kind of dental implant they hope will eventually feel and function like real teeth — right down to sending signals to the brain. “They lack the nerve elements that natural teeth have.” That’s how Dr. Jake Jinkun Chen, professor of periodontology and director of the Division of Oral … Read more

Researchers turn urine into material for dental and bone implants

“This process to yield hydroxyapatite, or bone mineral, takes less than one day,” says David Kisailus, UC Irvine professor of materials science and engineering. (Photo courtesy: Steve Zylius / UC Irvine)

Scientists have developed a novel biomanufacturing method that converts human urine into hydroxyapatite—a high-value, biocompatible mineral commonly used in dental and bone implants. The process, led by researchers at the University of California, Irvine, involves genetically engineered yeast that transforms waste into hydroxyapatite (HAp), a calcium phosphate compound that can also be used to restore … Read more

UB research deepens understanding of oral disorders by targeting gene linked to tooth enamel

UB oral biology professor publishes pioneering tooth enamel study Research reveals how targeting gene could help correct oral disorders, prevent craniofacial birth defects

A University at Buffalo research team led by oral biologist Dr. Hyuk-Jae (Edward) Kwon has advanced the understanding of genetic disorders that weaken tooth enamel by turning off a gene known as KMT2D in mice. The study, published in the Journal of Dental Research, marks the first in-depth investigation identifying KMT2D as a key regulator in enamel formation … Read more

Ancient teeth and dental plaque reveal new clues about Denisovans, early human evolution

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Thanks to their durable structure — from enamel to plaque — teeth have once again shed light on the history of human evolution. In one study recently published in the Journal of Human Evolution, researchers suggest that uniform pitting on tooth enamel dating back two million years — seen in specimens from Paranthropus, Australopithecus, and … Read more

Study shows, for the first time, that smoking leaves a permanent mark in teeth

Cementum analysis of archaeological samples revealed the same ring disruptions in the teeth of smokers who died in the 18th and 19th centuries.

UK researchers initially set out to investigate whether cementum rings—similar to tree rings—could be used in forensic settings to estimate a person’s age when DNA is not available. But what they discovered was something entirely different. The study, published in the journal PLOS ONE, found that smokers and ex-smokers exhibited signs of disruption in the … Read more

ADA’s ‘ultimate goal’ in research collaboration: Quickly regenerate lost tissue to save teeth

The ADA and Brigham and Women’s Hospital are developing 3D-printed bone grafts that use inflammation-resolving molecules to regenerate tissue lost to periodontal disease.

The dental research community continues to explore innovative bioengineering techniques. In a new effort, the American Dental Association (ADA) is collaborating with Brigham and Women’s Hospital in Massachusetts to improve the regeneration of bone and tissue lost to periodontal disease. According to the WHO, about 19 per cent of the global adult population — more … Read more

Saving teeth can be better than replacing them, 20-year study shows

“Replacing a tooth is not necessarily better than saving it,” says Dr. Cortellini, one of the lead investigators. (iStock)

Saving teeth with severe bone loss through periodontal regeneration (PR) offers benefits equal to — or greater than — replacing them with dental implants or bridges, according to a study that tracked patients for two decades, the European Federation of Periodontology (EFP) reported. “The idea that a tooth with severe loss of bone must always … Read more

Depression linked to less diverse oral microbiome, NYU researchers find

The researchers say their findings are part of a broader effort to understand how the oral microbiome may influence not only mental health but also cognitive decline and dementia.

A lower diversity of microbes in the mouth—particularly bacteria—is associated with depression, according to a new study led by researchers at NYU Rory Meyers College of Nursing. An estimated five per cent of adults globally suffer from depression, according to the World Health Organization (WHO). Oral diseases affect nearly 3.7 billion people worldwide, and their … Read more

UK study of over 500,000 people finds gum disease tied to multiple chronic conditions

UK data of more than half million people shows gum disease sufferers more likely to have multimorbidity

A new study based on data from more than half a million people in the U.K. has found that individuals with signs of gum disease are more likely to experience multimorbidity — the presence of two or more chronic health conditions. The research, led by University College London (UCL), in collaboration with the universities of … Read more

Study: Dentures release microplastics during dental procedures, daily use

While dentures may release microplastics during use, research also suggests they could help protect older adults from cognitive decline.

Microplastics have been found in breast milk, infant formula and even in the placentas of unborn babies. Now, a new study shows that patients’ dentures release minimal microplastics (MPs) during daily use and dental procedures. “Denture resins release small amounts of MPs during daily use, which may accumulate in the oral cavity and other organs … Read more