U of T researchers test probiotics in everyday foods like yogurt to fight childhood cavities

Researchers identified Streptococcus salivarius — a naturally occurring oral bacterium also present in breast milk — as a promising candidate for a synbiotic formula to prevent cavities in children. (iStock)

University of Toronto researchers are testing whether probiotics infused into common foods such as milk or yogurt could help prevent childhood cavities — one of the world’s most widespread chronic diseases. Led by dentistry professor Céline Lévesque, the team is using synbiotics — a combination of probiotics and prebiotics — to determine if beneficial bacteria … Read more

UB researcher wins nearly $1M NIH award to use AI to fight against gum disease

Li’s project uses a form of advanced machine learning called manifold learning, which distills complex data into simplified patterns. (iStock)

A University at Buffalo postdoctoral researcher will use artificial intelligence (AI) to uncover how gum disease develops and progresses. Lu Li, a postdoctoral associate in the School of Dental Medicine’s Department of Oral Biology, has received a $993,098 Pathway to Independence Award (K99/R00) from the U.S. National Institutes of Health (NIH). The five-year grant will … Read more

Oral bacteria and fungi tied to higher pancreatic cancer risk, large cohort study finds

The team found three periodontal pathogens — Porphyromonas gingivalis, Eubacterium nodatum and Parvimonas micra — were associated with increased risk. (iStock)

A new cohort study of 122,000 adults reports that specific oral bacteria — and the fungal genus Candida — were linked with a higher risk of developing pancreatic cancer years later. Published Sept. 18 in JAMA Oncology by researchers at NYU Grossman School of Medicine and collaborators, the nested case–control analysis identified 445 people who … Read more

On the forehead: Spotted ratfish first animal documented to grow teeth outside the jaw, study finds

Spotted ratfish Hydrolagus colliei fish underwater in sea. (iStock)

A team of University of Washington scientists has discovered that spotted ratfish are the first known animal to grow teeth outside of the jaw. The research, published Sept. 4 in Proceedings of the National Academy of Sciences (PNAS), overturns earlier assumptions that the male spotted ratfish’s club-like, barbed structure between its eyes was used to … Read more

Researchers develop antibacterial dental resin that could extend the life of fillings and crowns

Restoration of teeth with filling-polymerization lamp alternate text for this image

A new resin technology developed with U.S. Department of Energy support promises to cut down on costly, repeat dental procedures. Dental restorations such as fillings and crowns often fail within five to seven years because of secondary tooth decay. But a Brazilian dentist-turned-researcher, now based in Oklahoma, has developed a groundbreaking adhesive resin that could … Read more

Researchers identify gene cluster that helps good oral bacteria outcompete cavity-causing strains

Microscopic blue bacteria background alternate text for this image

A UC Berkeley professor of chemical and biomolecular engineering has long aimed to distinguish good oral bacteria from the bad. But Wenjun Zhang’s quest is not straightforward. Researchers have found that bacterial species are not entirely good or bad. This is because individual species can have hundreds of strains that vary in their cavity-promoting qualities. … Read more

Teens who lose teeth nearly twice as likely to be bullied, study finds

Australian researchers say tooth loss in adolescence can have serious social and psychological impacts, not just dental ones.

Teenagers who lose teeth due to decay or injury are almost twice as likely to be bullied, according to new Australian research. The collaborative study by the University of Sydney and the University of Melbourne, published in JDR Clinical & Translational Research, analyzed data from more than 4,400 children in the Longitudinal Study of Australian … Read more

Sugar substitutes may protect teeth, but major study links most to faster cognitive decline

Sweet but risky? Study reveals sugar substitutes and cognitive decline are strongly linked.

Sugar substitutes have long been promoted as a healthier alternative to sugar. They don’t cause cavities the way sugar does, and some — like xylitol — may even reduce Streptococcus mutans, the bacteria behind tooth decay. Research has also shown they have little to no impact on blood glucose levels, making them popular for people … Read more

Maple compound and chamomile extract show promise in fighting cavities

New studies show compounds from maple and chamomile may help prevent cavities, offering a natural boost for oral health.

Natural ingredients commonly found in consumer products are increasingly being recognized for their ability to fight tooth decay. Two recent studies highlight the potential of chamomile extract and a compound derived from maple to help prevent cavities. Maple compounds Researchers at the University of Wyoming reported in Microbiology Spectrum in early August that a non-toxic … Read more

Dental fear rising in the U.S., study shows — yet most patients want treatment

When asked if they would be interested in a free, at-home treatment for dental fear, 71.2 per cent of those with moderate or severe fear said yes.

Nearly three out of four American adults fear going to the dentist, according to new research from the NYU College of Dentistry. Earlier studies, conducted decades ago, estimated that just over a quarter of the U.S. population experienced dental anxiety. The new study, published in the Journal of the American Dental Association (JADA) on Tuesday, … Read more

Well-controlled diabetes protects teeth as much as not having the disease, large study finds

The researchers noted that regular maintenance preserved more teeth than treatment-only care, regardless of age or diabetes status.

A major cross-sectional study reports that people with well-managed diabetes keep about as many natural teeth as those without diabetes — but poor glycemic control is tied to faster tooth loss. The research team from Shiga University of Medical Science, in collaboration with Sunstar, analyzed an employment-based Japanese health claims and check-up database covering 705,542 … Read more

Could tea tree oil help high-risk caries patients? Study finds strong anti-plaque effect

Tea tree oil significantly reduced caries lesions in rats, though its effect on the broader oral microbiome remains under study.

A new study suggests tea tree oil (TTO) could help patients at high risk of dental caries by inhibiting the growth of key oral bacteria and preventing biofilm formation. Published in Scientific Reports on Aug. 29, the research highlights TTO as a “potent antimicrobial agent against cariogenic bacteria,” potentially offering a natural alternative or complement … Read more

Study: Dental pulp stones suggest underlying systemic conditions such as diabetes

Dental pulp stones—calcified deposits in the tooth pulp—are typically asymptomatic and often go unnoticed. A recent study suggests these findings, along with carotid artery calcifications, may be more common in people with diabetes. Published on Aug. 4, 2025, in BMC Endocrine Disorders, researchers examined panoramic radiographs of 107 diabetic patients (67 women, 40 men; age range 25–64, mean 49.7) and compared them with radiographs from 300 healthy individuals (196 women, 104 men).

Dental pulp stones—calcified deposits in the tooth pulp—are typically asymptomatic and often go unnoticed. A recent study suggests these findings, along with carotid artery calcifications, may be more common in people with diabetes. Published on Aug. 4, 2025, in BMC Endocrine Disorders, researchers examined panoramic radiographs of 107 diabetic patients (67 women, 40 men; age … Read more

AI shows promise in predicting dental treatment durations

AI could help clinics reduce bottlenecks and improve scheduling.

Researchers from the University of Sulaimani in Iraq tested whether Artificial Intelligence (AI) could help predict how long dental procedures take. Their study, published in Nature on Aug. 23, suggests that AI could reduce delays and improve patients’ overall experience. What did the study find? AI was trained on 2,500 procedure records. Another 500 records … Read more

Thanks to oxygen trapped in dino’s teeth, scientists recreate prehistoric air from millions of years ago

A Tyrannosaurus rex roars in this illustration. Scientists analyzed fossilized teeth from dinosaurs like T. rex to reconstruct prehistoric air from millions of years ago.

Scientists have reconstructed the air dinosaurs once breathed by analyzing oxygen isotopes preserved in fossilized teeth. The research, published in PNAS on August 4, demonstrates how dinosaur teeth can provide unprecedented insight into Earth’s prehistoric atmosphere and the interplay between greenhouse gases and plant life. “Fossil tooth enamel can thus serve as a robust time … Read more

Scientists explore using hair keratin in toothpaste to repair tooth enamel

Keratin from wool is being developed for use in sustainable toothpaste. (Photo courtesy of King’s College London)

King’s College London researchers have discovered that keratin—a protein found in hair, skin and wool—can repair tooth enamel and arrest early decay by forming a protective, enamel-like coating. Their study, published in Advanced Healthcare Materials, found that when keratin extracted from wool is applied to the tooth and comes into contact with minerals in saliva, … Read more

$2.1M NIH grant renewed for UB dental professor studying Sjögren’s disease

Book with title Sjogren’s Syndrome on a table. alternate text for this image

With no U.S. Food and Drug Administration–approved treatments for Sjögren’s disease, which affects about 4 million people in the United States—predominantly women—the National Institutes of Health (NIH) has renewed a $2.1-million grant for a University at Buffalo dental professor, the university says. The autoimmune disorder, marked by severely reduced tear and saliva production, leaves patients … Read more

Scientists think toothpaste potential after discovering natural compound that destroys dental plaque

White and lilac cauliflower, broccoli cabbage from farm market on old rustic green table alternate text for this image

Scientists have identified a natural compound found in some cruciferous vegetables that not only has anti-cancer properties but also targets the oral microbial biofilms responsible for cavities. In a study published in Antibiotics, researchers found that 3,3′-Diindolylmethane (DIM), also known as bisindole and found in vegetables such as broccoli and kale, reduced biofilm formation by … Read more

Researchers learn from marine mollusks’ indestructible teeth, aim for industrial applications

Chiton, locally called Suck Rocks surround a West Indian Top Shell at Building Bay Beach Bermuda

With advances in bioengineering, researchers are continually looking to nature for materials with exceptional properties. Their latest focus is on marine mollusks called chitons and their ability to grow extraordinarily hard, wear-resistant teeth. Scientists from the University of California, Irvine, along with collaborators at Japan’s Okayama and Toho universities, have uncovered for the first time … Read more

Researchers use biowaste from bovine bone and eggshells to make longer-lasting dental implants

bovine and eggshells for implants alternate text for this image

A new study offers a promising approach to creating longer-lasting dental implants while reducing biowaste. Researchers from SUNY Polytechnic Institute, the University of Ghana, and Worcester Polytechnic Institute have developed a sustainable method to enhance the durability of titanium-based dental implants by repurposing biowaste from bovine bones and eggshells. Published in Scientific Reports, the research … Read more