Antioxidant in red and pink produce linked to lower severe gum disease risk

Lycopene is found in red and pink fruits and vegetables such as tomatoes, watermelon and grapefruit. (iStock)

A natural antioxidant called lycopene, found in red and pink fruits and vegetables such as tomatoes, watermelon and grapefruit, has been associated with a reduced risk of severe periodontitis in older adults, according to a new observational study published in The Journal of Nutrition, Health & Aging. Periodontitis is a chronic inflammatory gum disease that … Read more

Natural amino acid in saliva shows promise in reshaping harmful dental plaque

Researchers say arginine could be safely incorporated into toothpastes or oral rinses, particularly for patients at higher risk of cavities — including children. (iStock)

Researchers testing a naturally occurring amino acid found in saliva say it could help make dental plaque less damaging — and potentially reduce the risk of cavities before they start. In a small human clinical trial, scientists from Aarhus University found that arginine, an amino acid already present in the mouth, can alter dental plaque … Read more

Researchers find Atlantic wolffish teeth contain rare material that shrinks under pressure

The Atlantic wolffish is known for its powerful bite, capable of crushing hard-shelled prey. (iStock)

Researchers at Hebrew University of Jerusalem have discovered that the Atlantic wolffish’s teeth contain a rare internal material that contracts in every direction when compressed — a mechanical behaviour almost never seen in natural mineralized tissues. The study, led by Prof. Ron Shahar of the Koret School of Veterinary Medicine at Hebrew University, found that … Read more

Nine U.S. universities launch $17M NIH study to advance TMD treatment

Five University at Buffalo researchers are involved in the study, known as the Collaborative for REsearch to Advance TMD Evidence (CREATE), which forms part of the broader TMD IMPACT research network. (iStock)

Nine U.S. universities are collaborating on a five-year, $17-million research initiative aimed at improving the understanding, diagnosis and treatment of temporomandibular disorders (TMDs), following a major grant from the National Institutes of Health (NIH). The multi-institution project, funded through the National Institute of Dental and Craniofacial Research (NIDCR), brings together researchers across dentistry, medicine, neuroscience, … Read more

Tooth loss — not diet — linked to cognitive decline in aging mice

Mice that lost their molars showed significant memory impairment — even when their protein intake matched that of control animals. (iStock)

A study published in Archives of Oral Biology suggests that tooth loss — rather than reduced protein intake — plays a central role in driving cognitive decline in aging male mice, underscoring a growing link between oral function and brain health. Low protein intake has long been linked to frailty, muscle loss and cognitive impairment … Read more

Study links periodontal bacterium to multiple sclerosis disability severity

The Hiroshima University researchers note that MS prevalence in Japan has risen over recent decades, a trend thought to be influenced by environmental changes. (iStock)

A Hiroshima University study has found that higher levels of the periodontal bacterium Fusobacterium nucleatum in the mouth were associated with greater disability in people living with multiple sclerosis (MS), though the researchers caution the findings do not establish cause and effect. The cross-sectional observational study, published in Scientific Reports, analyzed tongue-coating samples collected from … Read more

A year in review: Why 2025 showed oral health matters far beyond the mouth

"Specialists who deal with inflammatory diseases are starting to recognize the connections to oral health,” says Dr. Thomas Van Dyke. (iStock)

The year 2025 may be remembered as the moment oral health moved beyond the mouth — and into the centre of systemic disease prevention. As Dr. Thomas Van Dyke noted at SmileCon in October, dentistry and medicine have historically evolved on parallel tracks. But in 2025, a growing body of research brought those worlds closer … Read more

The growing link between oral health and sleep — from the oral microbiome to sleep apnea care

Interrupted breathing during sleep affects an estimated 30 million people in the United States. (iStock)

Dentistry’s role in sleep health is expanding — not just clinically, but biologically — as emerging research links sleep duration to oral microbiome diversity and evidence grows around sleep’s impact on periodontal health. Experts also are calling on dentists to take a larger role in sleep disorder care. At the American Dental Association’s Sleep and … Read more

Dental researchers target bacterial communication to shape healthier oral microbiomes

Bacterial communication — known as quorum sensing — allows microbes to detect their population density and coordinate community behaviour. (iStock)

Dental researchers are exploring how bacterial “conversations” in the mouth shape the ecology of dental plaque — and how interrupting those signals could favour a healthier microbial balance without harming beneficial species. A team from the College of Biological Sciences and the School of Dentistry at the University of Minnesota has detailed how bacterial communication … Read more

Dental calculus reveals hidden millet consumption in medieval Ukraine

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Move over bones — dental calculus is emerging as a new frontier in uncovering hidden elements of ancient diets. Using an advanced analytical method, researchers examining calcified dental plaque from medieval human remains at the Ostriv archaeological site in central Ukraine identified direct molecular evidence of millet consumption in people once thought unlikely to have … Read more

Australian study finds AI-backed dental scanner matches visual exams for early childhood decay

Early detection of tooth decay is critical in young children. (iStock)

Australian researchers report that a wireless intraoral scanner resembling an enlarged electric toothbrush, paired with AI-assisted software, can identify early childhood tooth decay as accurately as standard visual exams. The study, led by the Murdoch Children’s Research Institute (MCRI) and the University of Melbourne, evaluated 216 five-year-olds from the Melbourne Infant Study: BCG for Allergy … Read more

Researchers spotlight garlic extract mouthwash as possible alternative to chlorhexidine

A new review finds high-concentration garlic extract shows antimicrobial effectiveness comparable to chlorhexidine. (iStock)

Garlic’s pungent smell may not make it an obvious candidate for a mouthwash, but a new review suggests the bulb’s extract could offer a promising antimicrobial alternative to chlorhexidine. The findings, published this month in the Journal of Herbal Medicine, highlight growing interest in plant-based formulations as concerns mount over side-effects and long-term antimicrobial resistance … Read more

Bariatric surgery raises risk of gum and tooth disease — researchers urge integrated dental care

Nearly 600,000 bariatric procedures were recorded worldwide in 2023, according to IFSO. (iStock)

A new study in the International Dental Journal suggests patients who undergo bariatric surgery (BaS) face a significantly increased risk of periodontal and dental disease — prompting calls for integrated medical–dental aftercare. Although bariatric surgery is often hailed for dramatic weight loss and metabolic benefits, the authors note mounting evidence of unintended consequences for oral … Read more

Low maternal vitamin D tied to early childhood cavities — large Chinese cohort finds link

Previous research had linked maternal vitamin D deficiency to enamel defects and early caries in children — but results varied across studies and populations. (iStock)

A new prospective study of more than 4,100 mother–child pairs suggests that maternal vitamin D status during pregnancy may play a significant role in shaping children’s early-life dental health — with low vitamin D linked to notably higher odds of early childhood caries (ECC). Researchers from Zhejiang University followed 4,109 pregnant women (enrolled between 2011 … Read more

Study links typical fluoride exposure to modestly better cognitive performance in U.S. adolescents

Public-health agencies in both Canada and the United States recommend an optimal fluoride concentration of 0.7 mg/L. (iStock)

U.S. children exposed to fluoride concentrations typical of community water systems show “modestly better” cognitive performance in secondary school, according to a new national study. Published Nov. 19 in Science Advances, the study—“Childhood fluoride exposure and cognition across the life course”—examined data from the nationally representative High School and Beyond cohort, which followed 26,820 students … Read more

Analysis links gum disease to higher risk of erectile dysfunction

More men than women have gum disease. (iStock)

Severe gum disease may significantly increase the risk of erectile dysfunction, adding to growing evidence that oral health is closely linked to overall wellbeing, according to new analyses highlighted by the European Federation of Periodontology (EFP). Periodontitis — an advanced form of gum disease — has long been associated with diabetes, cardiovascular disease, rheumatoid arthritis … Read more

Mothers’ cortisol levels during pregnancy tied to faster baby teething, study finds

The timing of a baby’s first teeth may be shaped by hormone changes in late pregnancy, (iStock)

A new U.S. study suggests the hormonal environment of late pregnancy may influence when babies cut their first teeth — a finding researchers say could help explain why eruption timelines vary so widely in early childhood. The prospective cohort study, published in Frontiers in Oral Health, followed 142 mother–child pairs from late pregnancy through the … Read more

Study: Root canal treatments linked to better glucose control and lower systemic inflammation

Successful root canal therapy lowers glucose levels and inflammation markers tied to diabetes and heart disease. (iStock)

Yet another clinical study is adding to growing evidence that oral infections can affect the whole body. Researchers from King’s College London report that patients with chronic root canal infections who received successful endodontic treatment showed improved blood sugar control, better lipid profiles and reduced systemic inflammation over two years. “Long-standing root canal infections can … Read more

US$6M in new NIH funding to find treatment for ‘growing’ oral cancer and its pain relief

Oral squamous cell carcinoma develops in the lining of the mouth and makes up more than 95 per cent of all oral cancer cases, underscoring the urgent need for new therapies. (iStock)

Researchers at the UT Health San Antonio School of Dentistry have secured three National Institutes of Health (NIH) grants totalling US$6 million to improve oral cancer therapies, prevent treatment-related complications and develop better pain-relief strategies. Oral squamous cell carcinoma accounts for more than 95 per cent of oral cancer cases and carries a five-year survival … Read more